This course offers a systematic engineering design methodology: Stanford Design Thinking for preparing global startup. The course empathizes the whole Stanford design thinking process, “Empathy-Define-Ideation-Prototype-Test,” for building a startup with a business model that has a “customer truly need” component. This course focuses on lean “Prototype and Test” stages in Stanford Design Thinking. For this, the course introduces a novel manufacturing methodology by using 4th Industrial Revolution technology such as FaaS (Factory as a service) with AI, Bigdata, and 3D Printing. As a final achievement of this course, students will make their critical tools such as one-liner, lean-canvas, and global IR (investor relations) pitch deck for the first step of a global innovative startup founder. Although the lectures are designed to be self-contained, we recommend (but do not require) that students refer to the book E. Ries, The Lean Startup, Crown: New York, 2011/T. Hopkins, Selling for Dummies, Wiley: Indianapolis, 2011, and The Mechanical Design Process, D.G. Ullman, 4th Ed, McGraw-Hill, 2010, which can be helpful for this course.